Themes for innovation

Cancer

The LUMC is at the forefront of cancer research across a variety of domains. Our research encompasses the study of genetic risks and methods of primary prevention, the elucidation of oncogenic mechanisms, the innovation of diagnostic tools and therapeutic approaches, and the investigation into post-treatment care and welfare of cancer survivors.
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Vision & mission

The LUMC is actively engaged in conducting exceptional basic and translational research in the fields of cancer immunology and immunotherapy, DNA repair and genomic instability, as well as cancer cell signaling and biology. In addition, the institution excels in clinical research, with a strong focus on hereditary cancers, bone and soft tissue tumors, (uveal) melanoma, gynecological cancers, cutaneous lymphomas, hematological cancers, and other areas. Over the years, the LUMC has made significant contributions to the advancement of molecular and image-guided diagnostic tools. The institution has also conducted trials exploring a wide range of therapeutic approaches, including surgery, chemotherapy, radiotherapy, and immunotherapy. Research of the Theme "Cancer" is intrinsically linked to the LUMC Oncology Center (LOC).

Aims:

  • attract, foster and manage scientific talents, who are future world-leading researchers,
  • stimulate interaction between researchers and clinicians, thereby promoting the crossover of expertise,
  • increasingly couple cancer research to patient care and population health.

About us

 

Haico van Attikum.jpgHaico van Attikum

Haico van Attikum is full professor of Human Genetics and head of the Chromatin and DNA Repair group at the Leiden University Medical Center. His group studies the DNA damage response (DDR), which is a network of cellular pathways that sense, signal and repair DNA lesions to prevent genome instability diseases such as cancer. His group employs a cross-disciplinary systems biology-based approach that encompasses genetics, proteomics, microscopy and bioinformatics in yeast, mouse and human/patient cells to identify the proteins that constitute DDR pathways, and study their impact on genome stability maintenance and cancer.

Click here for profile Haico van Attikum.

Noel de Miranda.jpgNoel de Miranda

Noel de Miranda is the principal investigator of the Cancer Immunogenomics group at the Leiden University Medical Center. His group combines the use of high-end genomic, transcriptomic, and proteomic technologies for the study of cancer genetics and immunology. The main aim of his group is to support the development of novel therapies to enrich the immunotherapy toolbox for the treatment of advanced cancers. The group’s activities are subdivided into two major pillars: 1) the discovery of immunotherapeutic targets in cancer patients that are not amenable to state-of-the-art immunotherapies and 2) the identification of (innate) immune cell subsets with immunotherapeutic potential.

Marije Slingerland

Marije Slingerland is medical oncologist at the Leiden University Medical Center (LUMC) with a special interest in upper gastro-intestinal and head-and-neck cancer. Her research primary focuses on upper gastrointestinal cancer. She is a principal (co-)investigator of international and national clinical trials in gastro-intestinal and head-and-neck cancer. Next to being an oncologist she fulfills several other positions. The most important ones are vice president of the Dutch section medical oncology, board member of the DRCP, member of the committees BOM and DAP, member of the ESTRO esophageal guidelines committee, member of the Dutch gastric cancer, esophageal cancer and head and neck cancer guidelines and member of the scientific committee of the DUCG and the DUCA.

In addition to that she is the trainer Medical Oncology at the LUMC.
Recently she fulfilled the positions of treasurer of the board of the NVMO and board member of the DUCG.

Sub themes

Committees

Event committee:

  • Cor Ravensbergen, PhD student, department of Surgery.
  • Lisa Pagan, PhD student, Centre for Human Drug Research.
  • Igor Radanovic, PhD student, Centre for Human Drug Research.
  • Weixin Liao, PhD student, department of Cell and Chemical Biology.
  • Dr. Luuk Hawinkels, Associate Professor, department of Gastroenterology.
  • Dr. Erik van den Akker, Assistant Professor, department of Molecular Epidemiology.
  • Tassilo Wachsmann, PhD student, department of Hematology.
…

Event committee:

  • Cor Ravensbergen, PhD student, department of Surgery.
  • Lisa Pagan, PhD student, Centre for Human Drug Research.
  • Igor Radanovic, PhD student, Centre for Human Drug Research.
  • Weixin Liao, PhD student, department of Cell and Chemical Biology.
  • Dr. Luuk Hawinkels, Associate Professor, department of Gastroenterology.
  • Dr. Erik van den Akker, Assistant Professor, department of Molecular Epidemiology.
  • Tassilo Wachsmann, PhD student, department of Hematology.

Communication committee:

  • Dr. Marije Slingerland, senior medical specialist, department of Medical Oncology.
  • Dr. Agustin Enciso Martinez, postdoc, department of Chemical and Cell Biology.
  • Dr. Jessica Roelands, postdoc, department of Pathology.
  • Nadine van Montfoort, Assistant Professor, department of Gastroenterology.

Opportunities

Contact

cancer@lumc.nl