Postdoctoral Researcher
N. Bogunovic
Even voorstellen
I am specialized in cardiovascular transcriptional regulation and 3D disease modeling.
After completing my Master’s degree in Experimental Physiology at the University of Belgrade in Belgrade, Serbia, I relocated to Amsterdam to start her PhD in a collaboration between the departments of Vascular Surgery, Physiology and Clinical Genetics at the VUmc. Here I investigated the role of aortic smooth muscle cell dysfunction in the pathophysiology of aortic aneurysms by developing new models and methods to study smooth muscle cell impairment. I developed a new method to transdifferentiate skin cells into smooth muscle cells and a 3D co-culture model to study the interaction of smooth muscle cells and endothelial cells with the extracellular matrix in a in vitro model of aortic aneurysm. I also developed a new method to measure smooth muscle cell contraction and discovered a subgroup of patients with impaired smooth muscle cell contraction, associated with smoking.
After completing my Master’s degree in Experimental Physiology at the University of Belgrade in Belgrade, Serbia, I relocated to Amsterdam to start her PhD in a collaboration between the departments of Vascular Surgery, Physiology and Clinical Genetics at the VUmc. Here I investigated the role of aortic smooth muscle cell dysfunction in the pathophysiology of aortic aneurysms by developing new models and methods to study smooth muscle cell impairment. I developed a new method to transdifferentiate skin cells into smooth muscle cells and a 3D co-culture model to study the interaction of smooth muscle cells and endothelial cells with the extracellular matrix in a in vitro model of aortic aneurysm. I also developed a new method to measure smooth muscle cell contraction and discovered a subgroup of patients with impaired smooth muscle cell contraction, associated with smoking.
Wetenschappelijk onderzoek
I obtained a personal grant from the Amsterdam cardiovascular Sciences (ACS) institute to develop my own research line as a postdoctoral researcher. Shifting focus from the dysfunction of smooth muscle cells to the regulatory mechanisms behind it, I studied transcriptional regulation and gene expression patterns.
I joined the laboratory of Experimental Cardiology in March 2021, to uncover new ways to regenerate the heart within the RegMed XB cardiovascular moonshot project.
I joined the laboratory of Experimental Cardiology in March 2021, to uncover new ways to regenerate the heart within the RegMed XB cardiovascular moonshot project.
