PhD Student
MSc. I.Z.M. Kreuger
Area(s) of expertise:
Oncology, Cell biology, Melanoma, CDKN2A(p16) mutation
Oncology, Cell biology, Melanoma, CDKN2A(p16) mutation
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Introduction
In 2021, I completed my masters in Biomedical Sciences at the University of Amsterdam. During my education, I became intrigued by the mechanisms underlying cancer development and the different ways to study them. Therefore, I specialized in oncology and took additional courses in bio-informatics.
Previously, I did two research internships: one in the Oncogenomics group at the Netherlands Cancer Institute and another at the Dermatology department in the LUMC. During these internships, I studied the protein synthesis in cancer cell lines and delved into the development of aggressive cutaneous lymphoma.
Currently, I work as a PhD student at the Dermatology department and the Leiden Center for Computational Oncology, where I investigate (familial) melanoma.
Previously, I did two research internships: one in the Oncogenomics group at the Netherlands Cancer Institute and another at the Dermatology department in the LUMC. During these internships, I studied the protein synthesis in cancer cell lines and delved into the development of aggressive cutaneous lymphoma.
Currently, I work as a PhD student at the Dermatology department and the Leiden Center for Computational Oncology, where I investigate (familial) melanoma.
Scientific research
Our research focuses on better understanding the development of (familial) melanoma in order to identify novel targeted therapies and prevention strategies. In particular, we are interested in the role of the CDKN2A gene, which is frequently inactive in people with a hereditary predisposition for developing tumors. For our research, we make use of modified melanocytic cells, melanoma cell lines and skin tissues, which are analyzed using various techniques including omics and screens.
