Musculoskeletal radiology (oncology and rheumatology)

MSK oncology: Bone and soft tissue sarcoma

We are a tertiary bone and soft tissue sarcoma center with a dedicated multidisciplinary team. We are working together internationally in several areas, for example on osteosarcoma (within the FOSTER consortium), tenosynovial giant cell tumor of the tendon sheath (with LKEB, orthopedics, medical oncology and AmMax), chondrosarcoma (with a radiology and AI group from Milan), giant cell tumors of bone, osteosarcoma and Ewing sarcoma (with a radiology group in Gent).

Within the LUMC we are working on diffusion weighted imaging in characterization of neurogenic tumors (with the neurosurgery department) and on radiological differences between different spinal tumors such as chordoma and chondrosarcoma (with the radiotherapy department): CHIPT study. Furthermore, an imaging study on prostate cancer metastases is currently being analyzed (MRI whole body and PET CT) together with the oncology department (CHENA study).

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Within the LUMC we are working on diffusion weighted imaging in characterization of neurogenic tumors (with the neurosurgery department) and on radiological differences between different spinal tumors such as chordoma and chondrosarcoma (with the radiotherapy department): CHIPT study. Furthermore, an imaging study on prostate cancer metastases is currently being analyzed (MRI whole body and PET CT) together with the oncology department (CHENA study).

We are collaborating with the AVL in the SADDRIN-1 and SCOPES trials, neoadjuvant (chemo)radiotherapy studies in soft tissue sarcoma.

Our goals for the near future are to implement structured reporting for bone and soft tissue tumors, so that data can be drafted from radiology reports directly into the MDT form and used for (big data/radiomics) research, in combination with histopathology data.

In addition, we aim to make updated response evaluation criteria for Ewing sarcoma and osteosarcoma based on advanced MRI (diffusion weighted imaging and perfusion) and volumetric analyses.

Themes for Innovation

Key publications

Team members

  • Prof. J.L. Bloem, MSK radiologist
  • Dr. K. van Langevelde, MSK radiologist
  • Drs. A. Navas Canete, MSK radiologist
  • Prof. M.A.J. van de Sande, orthopedic surgeon
  • Prof. R.L.M. Haas, radiotherapist
  • Dr. A.D.G. Krol, radiotherapist
  • Prof. A.J. Gelderblom, medical oncologist
  • Prof. J.V.M.G. Bovée, pathologist
  • Dr. J.L. Groen, neurosurgeon