Head of Department, Clinical Epidemiologist

Prof. dr Frits R. Rosendaal

Area(s) of expertise:
Clinical Epidemiology
Introduction
Prof. Rosendaal studied medicine in Rotterdam, and obtained his PhD in Leiden (1989), with a thesis on haemophilia, and was appointed professor in 1997. His research is mainly focused on causes of cardiovascular disorders. He initiated several epidemiological studies, such as LETS and MEGA, that led to the discovery of a large number of causes of thrombosis, such as Factor V Leiden. An important long-standing research line is on the safety of hormonal drugs, notably oral contraceptive drugs, with regard to venous thrombosis. He developed models to understand how thrombosis occurs as a multicausal disorder, and to evaluate the quality of oral anticoagulant treatment. He takes part in large international consortia that search for genetic causes of several frequent disorders. He is initiator of the NEO-study (Netherlands Epidemiology of Obesity) in which 6700 individuals with overweight have been extensively examined and are followed through time. He is co-chair of the Committee on Scientific Integrity of LUMC and Leiden University.
Scientific research
Frits Rosendaal received several prestigious awards, such as the C.J. Kokprijs from Leiden University (1993), the Millennium Prize from the Universiteit of Trondheim, Norway (1999), de CARIM prize of the University of Maastricht (2002), de Spinozaprijs (2002), the Sol Sherry Award of the International Society on Thrombosis and Haemostasis (2003), the Distinguished Career Award of the International Society on Thrombosis and Haemostasis (2005), the Ham-Wasseman lecture of the American Society of Hematology, and an honorary doctorate from the University of Paris Descartes. He is elected fellow of the Royal Academy of Science and Arts (2008), of the German Academy Leopoldina (2011), and of the Academia Europaea.

He is chairman of the Policy Group of the European League of Research Universities (LERU), member of the Council of the Committee on Publication Ethics (COPE) and Editor in Chief of het Geneesmiddelenbulletin (Ge-Bu) and the journal Research Integirty and Peer Review (RIPR).

Publications