PhD-student Immunology

About your role

As a PhD student in Immunology, you will be responsible for investigating how the regulation of RNA translation influences T cell differentiation and their capacity to combat infections and cancer. Your research will focus on understanding the critical processes that enable naïve T cells to transit from a quiescent state into active proliferation, thereby acquiring specialized effector functions. This position requires utilizing advanced molecular biology techniques and provides an opportunity to contribute valuable insights into T cell responses that could enhance immunotherapy strategies. Your key responsibilities include:

• Conducting experiments using CRISPR-Cas9 gene editing, ribosomal profiling and proteomics to explore regulation of RNA translation in T cells. 
• Culturing primary T cells and employing spectral flow cytometry to analyze T cell differentiation and effector functions. 
• Analyzing data and integrating bioinformatics to understand the molecular mechanisms behind T cell fate decisions.

This position is embedded within a dynamic and collaborative international team at the LUMC, providing access to state-of-the-art facilities and resources. You will receive mentorship to support your personal and professional growth, making this an excellent opportunity for impactful research in the field of immunology.

About your workplace

The LUMC is a leading research and teaching hospital dedicated to advancing healthcare through innovative diagnostics and therapies for immune-related diseases. With a strong emphasis on translational research, the Department of Immunology plays a crucial role in understanding the complexities of the immune system and developing new treatment strategies.

At the department, you will work alongside leading scientists and clinicians who are dedicated to improving diagnostics and therapies for immune-related diseases. The emphasis on translational research ensures that discoveries made in the lab are swiftly applied to clinical practice, ultimately benefiting patients. Additionally, the department hosts regular seminars, workshops, and collaborative projects that encourage knowledge sharing and professional growth. The supportive atmosphere promotes both individual and collective achievements, making it an inspiring place to advance your career in immunology.

About you

To thrive in this role, you demonstrate a proactive attitude and strong organizational skills while paying meticulous attention to detail. You work effectively both independently and as part of a collaborative team, eager to contribute your insights and expertise. Further, you possess:

• A Master’s degree in biomedical sciences, molecular life sciences, biochemistry, or a related field.
• Theoretical and practical knowledge in immunology, molecular biology, or bioinformatics.
• An interest in molecular mechanisms and proficiency in bioinformatics, with an article 9 registration and willingness to engage in animal work considered advantageous.

Our offer

Driven by health; that's our mission. This applies not only to our patients but also to our employees. With Future@Work, we guarantee a pleasant working environment and provide room for development. In order to be able to continue to learn and develop, we offer internal and external training. You are also entitled to an end-of-year bonus (8,3%), holiday allowance, sports budget, bicycle scheme and reimbursement for commuting expenses. Furthermore, as an employee of LUMC, you are also affiliated with the ABP pension fund. This means that 70% of your pension premium is paid by LUMC, leaving you with a higher net salary. Nice, right?

See all employment conditions of the LUMC.

What do we represent?

Our health is our greatest asset. Unlike any other profession, in healthcare, you can fully appreciate the entire spectrum of humanity in all its breadth. LUMC, as an academic medical center, wholeheartedly embraces that diversity! We strive for the highest quality in healthcare, education, and (international) research. We aim to be a creative and inspiring workplace. It is essential that everyone feels at home, safe, and recognized. That is why the LUMC was the first academic medical center to partner with Workplace Pride. Our active network, LUMC Pride, is dedicated to optimal inclusivity and diversity within our organization. Regardless of origin, gender, appearance, age, identity, orientation, (physical) disability, or faith, you are a valuable part of our organization. Together, we are LUMC.

More information

• As a PhD-student, your salary will be between € 3,017 and € 3,824 gross per month (scale PRO, CAO UMC). These figures are based on a full-time position.
• The interview process includes two rounds. The first round is a one-to-one digital meeting with the group leader, scheduled for the week following the application deadline. Candidates who advance will be invited to LUMC for the second round, where they will give a presentation, meet the team, and tour the workspace.
• Applications from employment/recruitment agencies will not be considered.